🔓 Now Open — First Period Applications

Apply via Email → View Open Positions ↓

🔓 Now Open — Team Member Applications

🌍 International applications are open — any country, any university

Choose a Committee ↓

Zero Waste Policies of Pharmaceuticals in Turkey

Table of Contents

1. 1.What is Pharmaceutical Waste and What are Turkey's Main Pharmaceutical Zero-Waste Policies?
2. 2.5-Step Guide to Pharmaceutical Waste Disposal
3. 3.Turkey's Current Goals in Improving Pharmaceutical Waste Disposal
4. 4.Data and Tracking in Pharmaceutical Zero Waste
5. 5.What Would Happen if the Pharmaceutical Waste Disposal System Had Ceased to Exist?
6. 6.The Role of Municipalities in Collecting and Processing of Pharmaceutical Waste in Turkey
7. —References

What is Pharmaceutical Waste and What are Turkey's Main Pharmaceutical Zero-Waste Policies?

What is pharmaceutical waste?

Pharmaceutical wastes are simply drugs and medicines that can no longer be used. They may be generated by a range of activities and locations in healthcare facilities, including pharmacies, distribution centres and hospitals. Pharmaceutical waste also contains contaminated pharmaceuticals, such as vaccines, as well as spent biological products for therapy and transdermal patches.

Turkey's approach to pharmaceutical waste

Turkey has an extensive zero-waste policy towards pharmaceutical and medical waste. This includes broadly: separate collection of waste on the facility they're generated, temporary storage of the waste, and also the transport and disposal.

The color-coded segregation of waste materials (such as serum or medicine bottles being collected in blue recycling bags), strict incineration protocols (waste is only disposed in licensed, high-temperature incineration plants) are also important parts of Turkey's zero-waste policy. Additionally, local municipalities have set up medication waste collection bins in several community hubs, family health centers and similar locations.

5-Step Guide to Waste Disposal: How is the Disposal Process Handled?

Turkey's Current Goals in Improving Pharmaceutical Waste Disposal

The future plan for pharmaceutical waste management in Turkey aims to guide the country toward an increasingly circular and participatory model rather than a reactive one.

Led mainly by the Ministry of Environment, Urbanization and Climate Change in close collaboration with the Ministry of Health, Turkey's strategic objectives aim at strengthening institutional enforcement, making family-level collections part of daily life, and achieving ambitious sustainability targets.

One of the most important targets is improving the technology of waste processing equipment. The state is currently favoring high-efficiency, localized medical waste processing equipment — such as 304-grade stainless steel containment units — to eliminate micro-leakages during transit.

Plans like the 12th National Development Plan (2024–2028) and the newly updated National Circular Economy Strategy and Action Plan (UDESEP) released in late 2025 demonstrate Turkey's strict waste disposal improvement strategy. Facilities like İZAYDAŞ and İSTAÇ are being tasked with expanding their waste-to-energy infrastructure, ensuring that the thermal treatment of chemical compounds directly offsets national grid power usage.

Data and Tracking in Pharmaceutical Zero Waste

The Zero Waste Project system is an important approach for planning sustainable cities. It aims to prevent, reduce, reuse, and recycle waste. It is believed that approaches like the Zero Waste Project will contribute not only to preventing environmental pollution in a physical sense, but also have the potential to bring about social solidarity and economic improvement.

The Ministry of Environment and Urbanization launched the "Zero Waste" project in 2017. In the following years, regulations such as charging for plastic bags, deposit-refund systems, and the Paris Agreement were implemented into regular life in Turkey. With these regulations, it became obligatory for public institutions and organizations to adopt the Zero Waste Management System as of 1 June 2020.

When it comes to pharmaceutical waste, until 2009, a considerable amount was disposed of in landfills and covered with lime. The Zero Waste regulation explains how pharmaceutical waste will be collected and properly disposed of. According to this regulation, healthcare services such as hospitals, pharmacies and pharmaceutical warehouses are responsible for their pharmaceutical waste, and medicine waste generated by households is managed by municipalities. In Istanbul, the most populated city in Turkey, there are currently 39 district municipalities. Additionally, for districts that are far from the landfill, there are waste transfer stations with a capacity suitable for waste quantities and in places where route optimization is provided.

Currently, there are 104 transfer stations in Turkey, 59 of which are in metropolitan cities and 45 in non-metropolitan provinces. Since 2010, the number of municipal waste landfills has increased from 46 to 93. In addition, the proportion of the municipal population with landfill services increased from 59% to 89%. As of 2022, there are 9 incineration, 11 compost, and 2,866 recycling facilities.

In 2023, Pendik had the most amount of medicine waste collected by the Zero-Waste Project, collecting 7,460 kilograms of medicine waste in that year. However, out of 39 districts, only 18 shared their data on the amount of pharmaceutical waste collected in 2023.

According to the findings, although there was a 2% difference between cold medications and painkillers, no statistically significant difference was found (p<0.05). While the vitamin and statin group (cholesterol drugs) showed more disposal in the group with a high-income level, hormone drugs showed more disposal in the group with a lower income level. The fact that the antibiotic group was low in both groups shows that restricting access to antibiotics in line with the rational drug policy implemented in the country is effective. Since the period in which the research was conducted coincided with the COVID-19 pandemic, the number of wastage of drugs used in cold and flu infections increased. This indicates that hoarding habits led to unnecessary drug intake, and therefore an increase in waste drug amounts (15%). Consequently, different policies regarding rational drug use need to be developed.

When dosage forms of waste medicines are analyzed (Figure 3), it is seen that solid and liquid dosage forms take the first two places. In Group B, the amount of waste generated by liquid dosage forms is quite high. Considering that the majority of liquid dosage forms are in syrup form, it is concluded that the pediatric population is higher in this group. Wastes from creams or ointments, which constitute the semi-solid group, were found to be relatively less and in similar amounts in both groups. The fact that there were almost no products requiring a cold chain reveals that this group only took as much as they needed. Most of collected drugs were expired (56.75%), and disposed of with their original secondary container (46.25%). It is a matter of concern that 10.75% of the total quantity of waste pharmaceuticals was never used.

Waste management is a crucial process for all countries. Methods such as incineration and underground burial are employed for non-recyclable wastes, yet these practices have the potential to exacerbate various environmental concerns. A review of studies conducted for the pharmacy and pharmaceutical industry revealed that waste pharmaceuticals are increasingly prevalent in Turkey, with limited disposal options. Unused or wasted pharmaceuticals represent a significant global challenge. The health sector and the consumption of health-related products are growing rapidly. Unfortunately, there is currently no process for the recovery of the waste drug molecule. Consequently, on-site separation and waste minimisation methods are being applied or attempted in Turkey and around the world with the aim of reducing pharmaceutical waste.

What Would Happen if the Pharmaceutical Waste Disposal System Had Ceased to Exist?

If there were no specific use of thermal incineration or any kind of dedicated containment, hundreds of thousands of tons of outdated and unused medicines would be dumped into municipal landfills or flushed down toilets. Enormous doses of hormones (as present in combination pills), psychiatric medications (depressants, stabilizers) and cardiovascular drugs would pass completely unaltered through water treatment plants and enter household tap water.

Without means to lock up pharmaceuticals in pharmacy drop-boxes or destroy them, every single bottle of strong medications such as morphine and other opioid analgesics would end up in municipal trash cans and landfills. Wildlife, stray animals, and even farm animals near garbage dumps would inevitably ingest deadly combinations of pharmaceuticals.

The pharmaceutical manufacturing plant produces large quantities of chemically hazardous waste, off-specification batches and toxic solvents during synthesis. The resultant products and wastes would otherwise have to be stockpiled if it were not for permitted disposal methods.

The Role of Municipalities in Collecting and Processing of Pharmaceutical Waste in Turkey

Pharmaceutical waste is regularly disposed of in great amounts, especially in the bigger cities of Turkey. Consequently, municipalities are required to take on a great responsibility on waste disposal to prevent environmental hazards. According to Aydın's article published in 2019, "hospital waste consists of 3% chemical and pharmaceutical waste" which alone is a critical amount when the total number of hospitals in big cities is considered.

In İstanbul, a recent action was taken by Ataşehir municipality in order to improve the collection of pharmaceutical waste. The municipality placed over 140 waste medicine collecting boxes all around the district, and the collected waste which exceeded 660 kilograms in only 5 months was safely separated and sent to proper disposal centers.

Not only municipalities alone work for a better environment — the Istanbul Chamber of Pharmacists has also collaborated with the Beşiktaş municipality to place medicinal waste bins in pharmacies. The municipality has conducted an effective strategy by this collaboration since citizens are more likely to be aware of the waste bins, and it also allows for a healthcare professional, like a pharmacist, to inform patients about it. The collected pharmaceutical waste is then sent to special facilities like İSTAÇ for proper disposal.

İSTAÇ is a company which operates alongside the İstanbul Metropolitan Municipality with the aim of advancing the zero-waste movement. They have factories for waste disposal, and their services include medical waste management. Their primary methods of pharmaceutical waste disposal involve strictly guided incineration protocols, since a thermal destruction route is required for pharmaceutical waste — unlike certain other medical waste which can be disposed of via special steam sterilization autoclaves. It is of critical importance for the thermal destruction process to be done properly, since hazardous pharmaceutical waste can contaminate aquatic habitats, recreational lakes, or even purification facilities (Efendi et al., 2022), and thus lead to a serious environmental disaster.

Up until 2013, there was a singular facility to treat potentially hazardous waste, which was İzaydaş in İzmit. Since then, many specialists in environmental sciences have conducted research to predict the future of pharmaceutical waste, which is imperative for designing an effective waste management system (Aziz Kemal Konyalıoğlu et al., 2024).

In conclusion, it is of utmost importance to always improve the zero-waste movement, and to be aware as citizens of the possibly catastrophic consequences of recklessness about improper pharmaceutical waste disposal, as well as how to fulfill responsibilities by using the many services Turkey's municipalities have provided and continue to provide.

Full Reference List

1. EPA. (2024, September 11). Resource Conservation and Recovery Act (RCRA) Overview. United States Environmental Protection Agency. https://www.epa.gov/rcra/...
2. Wilson, D. C. (2015). Global Waste Management Outlook. UN. https://wedocs.unep.org/...
3. Sağlık Kuruluşlarında Tıbbi Atık Yönetimi (Çevre ve Şehircilik İl Müdürlüğü). webdosya.csb.gov.tr/...
4. TIBBİ ATIKLARIN KONTROLÜ YÖNETMELİĞİ (TC Cumhurbaşkanlığı Resmi Gazete). mevzuat.gov.tr/...
5. Vertisa. Tıbbi Atık Bertaraf Yöntemleri. vertisa.com.tr/...
6. İBB Atık Yönetimi. Tıbbi Atıkların Toplanması ve Bertarafı. atikyonetimi.ibb.istanbul/...
7. İSTAÇ. Atık Yönetimi. istac.istanbul/...
8. Aydoğan, Ö., Varank, G., & Bilgili, M.S. (2011). Medical waste management in Gaziantep. Journal of Engineering and Natural Sciences / Sigma, 3, 132–140.
9. Mollamahmutoğlu, A., & Bekmezci, S. Türkiye'de tıbbi atık yönetimi, bertarafına yönelik son gelişmeler ve Ankara'daki uygulamaları. İnşaat Mühendisleri Odası (İMO).
10. Henden Şolt, H.B. (2023). Evaluation of the Zero Waste Project in Istanbul District Municipalities from the Perspective of Sustainable Urban Planning. Sustainability, 15, 11896. https://doi.org/10.3390/su151511896
11. Köksoy, S. (2024). Unused, expired pharmaceuticals and their disposal practices among the general public in Burdur-Türkiye. BMC Public Health, 24(1), 1303. https://doi.org/10.1186/s12889-024-18788-0
12. Saka, O.M. (2024). Investigation of the Prevalence of Expired and Unused Pharmaceuticals in the Ankara Region. Journal of Faculty of Pharmacy of Ankara University, 48(3), 835–839. https://doi.org/10.33483/jfpau.1473405
13. Yönten, E. et al. (2026). İlaç Atıklarının Çevreye ve Halk Sağlığına Etkileri, Geri Dönüşümü ve Mevzuat Çerçevesi. Journal of Anatolian Environmental and Animal Sciences. doi: 10.35229/jaes.1768361
14. Aydın, N. (2019). Hazardous Waste Management in Turkey. Journal of Anatolian Environmental and Animal Sciences, 4(3), 312–318. https://doi.org/10.35229/jaes.558213
15. Aziz Kemal Konyalıoğlu, Ozcan, T., & Ilke Bereketli. (2024). Forecasting medical waste in Istanbul using a novel nonlinear grey Bernoulli model optimized by firefly algorithm. Waste Management & Research. https://doi.org/10.1177/0734242x241271065
16. Efendi, S. et al. (2022). Pharmaceutical Waste Collection Management Using Location-Routing Model in a Reverse Supply Chain. Procedia Environmental Science, Engineering and Management, 9(3), 711–724. procedia-esem.eu/...
17. Atık İlaç | Beşiktaş Belediyesi. (2021). cevre.besiktas.bel.tr/...
18. 5 Ayda 660 Kilogram Atık İlaç Toplandı — T.C. Ataşehir Belediyesi. (2026). atasehir.bel.tr/...

Environmental Persistence of Pharmaceuticals: Pseudo-Persistence, Pathways, and Mitigation

Table of Contents

1. 1.Introduction
2. 2.Understanding Pseudo-Persistence
3. 3.Regulatory Frameworks and Mitigation Strategies
4. 4.Conclusion
5. 5.References

Section 1

Introduction

Traces of pharmaceuticals are increasingly detected in environmental compartments such as surface water, groundwater, and marine ecosystems due to continuous human and veterinary use and incomplete removal in wastewater treatment systems. These compounds enter the environment through various pathways including domestic sewage, hospital effluents, agricultural runoff, and improper disposal of medicines.

The presence of pharmaceuticals in the environment is an important public health and ecological concern, as many of these compounds remain biologically active even at low concentrations. Among their various detrimental consequences, these compounds can significantly affect non-target aquatic organisms, causing alterations in behavior, reproduction, growth, and endocrine function, contributing to ecological imbalance and biodiversity loss. This could potentially lead to long-term risks for human health through water contamination and bioaccumulation.

Section 2

Understanding Pseudo-Persistence

Section 3

Regulatory Frameworks and Mitigation Strategies

Section 4

Conclusion

Pharmaceutical residues represent an increasingly serious environmental concern, as they are continuously released into ecosystems and can remain biologically active even at very low concentrations. Many of these compounds exhibit pseudo-persistence, resulting in a broad and sustained presence in surface waters and other environmental compartments.

This situation poses significant risks for aquatic organisms, including disturbances in reproduction, growth, and microbial balance, as well as the potential emergence of antimicrobial resistance.

Addressing this challenge requires stronger regulatory frameworks, improved wastewater treatment technologies, and more responsible use and disposal of pharmaceuticals. Meaningful progress will depend on coordinated action that integrates policy measures with innovative treatment solutions — creating a sustained, long-term reduction in the environmental burden of pharmaceutical contaminants.

Section 5

References

Certificate Verification

Enter a PharmHive certificate code to verify its authenticity.

Certificate Code

Member Portal

Sign in to access your PharmHive profile

Sign In →

✕

‹ ›